Department of Chemistry

Name: Dr. Hira Khalid
Extension Number: 562
Email ID: hirakhalid@fccollege.edu.pk
Office Number: S-153

Dr. Hira Khalid is an Associate Professor at Forman Christian College University’s Department of Chemistry, with 15 years of teaching and research experience. Committed to improving chemistry education, Dr. Hira focuses on utilizing interactive and effective teaching practices to engage students and foster deeper understanding. As an experienced researcher in organic synthesis and medicinal chemistry, she has made significant contributions to drug design and development aimed at raising health industry standards and improving quality of life. Dr. Hira holds a PhD in Chemistry from GC University Lahore, Pakistan, in collaboration with the University of Washington, Seattle, USA

Education

Post-Doc (US Fulbright Scholar) Medicinal Chemistry, University of Minnesota Twin Cities, Minneapolis, USA

PhD Chemistry (HEC Indigenous scholarship & IRSIP Awardee) with specialization in Synthetic Organic and Medicinal Chemistry, GC University Lahore Pakistan in collaboration with University of Washington Seattle, USA

MS Chemistry with specialization in Analytical Chemistry, University of the Punjab, Lahore Pakistan

BSc Hons. Chemistry, University of the Punjab, Lahore Pakistan

RESEARCH & PUBLICATIONS

Dr. Hira’s research has led to the discovery and development of small molecules drug contenders for the Cancer, HCV, Alzheimer and infectious diseases. Her work has been published extensively in reputable scientific journals and she has been involved in numerous international collaborations that emphasize the synthesis and biological evaluation of medicinal compounds. She has published over 40 research articles in international journals, including Nature Communications, ACS Journal of Medicinal Chemistry, and RSC Advances, and is the author of an Elsevier book chapter, “Emerging Trends in Chemical Sciences.” Her recent projects include the design and synthesis of novel small molecule inhibitors for ovarian cancer treatment, selected in Phase I of Women in Science Program. She has awarded IRIF grants for her projects focusing on synthesis of heterocyclic polyfunctional compounds as potential anticancer agents and Design and synthesis of HCV-NS3 protease inhibitors. She is HEC approved Research supervisor. Dr. Hira is member of prestigious professional societies ACS, RSC, IUPAC, CSP and advisor ACS Punjab.

Selected Publications:

1. Muhammad Nawaz Shah, Hira Khalid*, Sabina Jhaumeer Laulloo, Nausheen Joondan, Muhammad Nadeem Arshad, Abdullah M. Asiri, Hassan Butt “Synthesis, Characterization, and BSA Binding studies of Newfangled 2-Phenylacetohydrazide derivatives” Heliyon, 2024, HELIYON-D-22-31658, Accepted.
2. Rashid Hussain, Zulkarnain Haider, Hira Khalid*, Qaiser Fatmi, Simone Carradori, Amelia Cataldi and Susi Zara “Computational medicinal chemistry applications to target Asian-prevalent strain of hepatitis C virus” RSC Advances, 13, 30052 2023
3. Erik B. Faber, Jian Tang, Emily Roberts, Sornakala Ganeshkumar, Luxin Sun, Nan Wang, Damien Rasmussen, Abir Majumdar, Kristen John, An Yang, Hira Khalid, Jon E.Hawkinson, Nicholas M. Levinson, Ernst Schönbrunn, Vargheese Chennathukuzhi, Daniel A. Harki, Gunda I. Georg “Allosteric, selective cyclin-dependent kinase 2 inhibitors are negatively cooperative with cyclin binding and show potential as contraceptive agents” Nature Communications, 14, 3213, 1-13 2023
4. Erik B. Faber, Nan Wang, Kristen John, Luxin Sun, David Burban, Henry Wong, Rawle, Francis, Defeng Tian, Kwon H. Hong, Liming Wang, An Yang, Mazen Elsaid, Jian Tang, Emily Roberts, Sornakala Ganeshkumar, Damien Rasmussen, Abir Majumdar, Hira Khalid, Nicholas M. Levinson, Ernst Schönbrunn, Jon E.Hawkinson, Gunda I. Georg “The discovery of high affinity and metabolically stable allosteric cyclin-dependent kinase 2 (CDK2) inhibitors from screening through lead optimization” ACS Journal of Medicinal Chemistry, 66, 3, 1928–1940 2023
5. Hira Khalid, Aziz-ur-Rehman, M. Athar Abbasi, Abdul Malik, Shahid Rasool, Khadija Nafeesa, Irshad Ahmad, Saira Afzal, ”Synthesis, spectral analysis and anti-bacterial study of N-substituted derivatives of 2-(5-(1(phenylsulfonyl)piperidin-4-yl)-1,3,4-oxadiazol2-ylthio)acetamide, Journal of Saudi Chemical Society, Vol 20, S615–S623, 2016